DEFINITE

Defibrillators in Non-Ischemic Cardiomyopathy Treatment Evaluation Trial

 

Objective:

Evaluate the effectiveness of ICD therapy (n = 229) compared to control therapy (n = 229) in non-ischemic cardiomyopathy patients

Primary endpoint:

• Overall Mortality

Secondary endpoint:

• Sudden death from arrhythmia

Status:

Start: July 1998
Completion: May 2003
Sample size: 458
Published: New England Journal of Medicine, May 2004¹

ICD Results:

• Reduced overall mortality by 35%
• Reduced arrhythmic mortality by 80%